Radiohead, "How To Disappear Completely"
In keeping with my "all Radiohead all week" theme (to celebrate the release of their new album In Rainbows, which you can download for whatever price you wish to pay on October 10th), here is a Radiohead song that makes you want to slit your wrists.
Ah! But then you realize, "If I slit my wrists, I can't listen to this song ever again" so you don't.
So, in a weird way it depresses you but then it makes you want to live.